Melanotan II – Health Benefits & Side Effects
Despite the fact that this drug is not prescribed for medical purposes, many people order it online. They pay a hefty price for an injection, but they’re still concerned about the side effects and safety of the drug. There’s simply not enough data about Melanotan to be sure that it is safe to use without a prescription. Before deciding to use it, you should consider the side effects and benefits of using Melanotan.
Long-term body mass loss without restricting calories
Researchers have shown that Melanotan 2 suppresses appetite, promotes weight loss and improves energy balance in mice. These results demonstrate that Melanotan II may prove to be an important tool against obesity. Further studies are needed to understand its mechanisms. In mice, Melanotan II inhibits the production of melanocortin hormones and can prevent fat storage.
It works by activating two molecular signaling pathways in the brain and altering the central melanocortin system. In animal models, Melanotan II causes weight loss without restricting calories. In humans, Melanotan II may also help change moles and freckles. It may also cause skin cancer. Although the use of Melanotan II has been controversial, its use in reducing body fat may benefit the health of people who want to lose body fat and reduce their risk of disease associated with aging.
Increased risk of pigmented skin cancer
A recent warning from the Austrian Medicinal Agency on the dangers of melanotan II, a topical sunscreen, has prompted the manufacturer to recall the product. While the document appears to be available only in German, the MHRA cites several links to the FDA and MHRA’s warnings regarding this chemical. The FDA warning for melanotan II cites the risks of sunbed exposure and bloodborne viruses.
Although the safety of Melanotan-II is unknown, it has been linked to an increased risk of cutaneous melanoma and a risk of melanoma. A recent case report involving a 20-year-old woman with Fitzpatrick skin type II presented to a dermatology clinic with a suspicious black melanocytic lesion in the left gluteal region. Upon excising the lesion, histology revealed that the patient had undergone a three to four-week course of MT-II. She had also conducted self-injections of MT-II and had undergone augmentation through sunbed tanning.
Increased risk of kidney infarction
A study published in JAMA Internal Medicine suggests that a nonselective melanocortin receptor agonist can increase the risk of kidney infarction in patients taking the drug Melanotan II. The compound acts on five different melanocortin receptor subtypes, all of which are found in the skin and adrenal cortex. The substance induces melanocytes to increase production of eumelanin. However, studies have been inconsistent regarding the exact mechanisms of Melanotan II causing renal infarction.
Although it’s not clear why melanotan 2 causes this condition, doctors have noted links between the drug and skin cancer cells. This is especially concerning when melanotan II is used by young people for tanning. Many social media influencers are now advertising melanotan II-based products on their channels. The chemical is found in a variety of forms, including oral sprays, nasal sprays, and injections.
